The liver is responsible for removing toxins from the blood, and it aids in storage of trace elements and glycogen, bile production and excretion. In conjunction with the liver, the kidney is another critical filter organ and is a major regulator of fluids and electrolyte balance. In combination, these organs are responsible for vitally important functions including producing hormones that affect the absorption of nutrition in the gut, blood pressure regulation, along with Vitamin D and red cell production.  All of these processes are critically important to the performance, health and well being of the horse.

The fall is typically when seasonal rise can effect a PPID status, possibly driving new or increased hyperinsulinemia and laminitis. The spring is a time when caregivers look to check their equine’s PPID and EMS diagnosis status, to determine if the treatment plan they have in place is effective.